Cholesterol reducer and thrombolytic therapy in acute ischemic stroke patients.
Nicolas PouporeDan StratTristan MackeyKatherine BrownAshley SnellThomas I NathanielPublished in: Lipids in health and disease (2020)
A prior cholesterol reducer, namely a statin, plus rtPA combination may be associated with worsening neurological function for elderly AIS patients with atrial fibrillation, while Caucasians directly admitted to a neurology unit are more likely to show an association with progress or improvements in neurologic functions. While combining statin with rtPA treatment may facilitate worsening neurologic functions in elderly AIS patients with atrial fibrillation, they should not be denied of this therapy. The decision to combine statin and rtPA for AIS patients with atrial fibrillation can be done after clinical stabilization following appropriate clinical management.
Keyphrases
- low density lipoprotein
- cardiovascular disease
- coronary artery disease
- liver failure
- pulmonary embolism
- community dwelling
- ischemia reperfusion injury
- drug induced
- stem cells
- bone marrow
- combination therapy
- cell therapy
- acute ischemic stroke
- blood brain barrier
- hepatitis b virus
- extracorporeal membrane oxygenation