Magnetic-optical dual-modality imaging monitoring chemotherapy efficacy of pancreatic ductal adenocarcinoma with a low-dose fibronectin-targeting Gd-based contrast agent.

Wenjia ZhangXiaolong LiangXinyu ZhangWei TongGuangyuan ShiHaozhuo GuoZhengyu JinZhenyu ZhangYang DuHuadan Xue

Published in: European journal of nuclear medicine and molecular imaging (2024)

MRI/FMI with a low dose of ZD2-Gd-DOTA-Cy7 enables sensitive imaging of PDAC and the quantitative assessment of fibrotic changes during AG chemotherapy, which shows potential clinical applications for precise diagnosis, post-treatment monitoring, and disease management.

Keyphrases

low dose
high resolution
high dose
contrast enhanced
locally advanced
magnetic resonance
pet ct
squamous cell carcinoma
computed tomography
quantum dots
radiation therapy
risk assessment
fluorescence imaging
combination therapy
molecularly imprinted
rectal cancer
replacement therapy
positron emission tomography