A Multicancer Malignant Pleural Effusion Diagnostic Test Using Hexokinase 2 and Single-Cell Sequencing.

Jie ChenYibin YangZhuo WangXiaohan ShenZiyuan ZhangChunying WangHaimiao XuQihui Shi

Published in: Clinical chemistry (2022)

HK2-seq establishes definitive MPE diagnosis across many cancer types with high diagnostic performance. It has the potential to be used for multicancer detection of circulating tumor cells in blood and other types of body fluids, as well as liquid biopsy-based genomic characterization for informative diagnosis.

Keyphrases

single cell
circulating tumor cells
rna seq
papillary thyroid
high throughput
circulating tumor
squamous cell
genome wide
copy number
squamous cell carcinoma
ultrasound guided
locally advanced
loop mediated isothermal amplification
real time pcr
radiation therapy
high glucose
quantum dots