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Autophagy dysfunction contributes to NLRP1 inflammasome-linked depressive-like behaviors in mice.
Ya-Jing Zhu
Jing Huang
Ru Chen
Yu Zhang
Xin He
Wen-Xin Duan
Yuan-Lei Zou
Meng-Mei Sun
Hui-Li Sun
Si-Min Cheng
Hao-Chuan Wang
Hao Zhang
Wen-Ning Wu
Published in:
Journal of neuroinflammation (2024)
Autophagy dysfunction contributes to NLRP1 inflammasome-linked depressive-like behavior in mice and the regulation of autophagy could be a valuable therapeutic strategy for the management of depression.
Keyphrases
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nlrp inflammasome
oxidative stress
cell death
endoplasmic reticulum stress
signaling pathway
bipolar disorder
high fat diet induced
depressive symptoms
type diabetes
wild type
metabolic syndrome