The amount of signet ring cells is significantly associated with tumour stage and survival in gastric poorly cohesive tumours.

Maria BencivengaElio TreppiediMariagiulia Dal CeroLorena TorroniGiuseppe VerlatoMar IglesiasFlorence RenaudAnna TomezzoliClaudia CastelliGuillaume PiessenManuel PeraGiovanni de Manzoni

Published in: Journal of surgical oncology (2020)

The percentage of SRCs was inversely related to tumour aggressiveness, with long-term survival significantly higher in SRC1 compared with SRC2 and SRC3 tumours.

Keyphrases

tyrosine kinase
induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
free survival
cell proliferation
drug induced