High-Impact Pain Is Associated With Epigenetic Aging Among Middle-Aged and Older Adults: Findings From the Health and Retirement Study.

Javier A Tamargo Larissa J Strath Yenisel Cruz-Almeida

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2024)

High-impact pain is associated with accelerated epigenetic aging among middle-aged and older adults in the United States. These findings highlight aging-associated epigenetic alterations in high-impact chronic pain and suggest a potential for epigenetic therapeutic approaches for pain management and the preservation of physical function in older adults.

Keyphrases

chronic pain
pain management
dna methylation
gene expression
physical activity
public health
neuropathic pain
social media
health information
risk assessment
climate change