TNF-alpha releasing capacity of the whole blood drops after open total splenectomy, but increases after partial/subtotal or minimally invasive splenectomy.
Mihnea P DragomirStefan TudorMonica LacatusOana StanciuleaBogdan TrandafirAdriana DiaconuDaniel CoriuAnca ColitaGabriela DrocRaluca Purnichescu-PurtanGeorge CalinCatalin VasilescuPublished in: Acta chirurgica Belgica (2021)
Splenectomy induces a decrease of the pro-inflammatory cytokine TNF-alpha and if splenic parenchyma is spared and the surgery is performed MI, this change is hindered.