Knockout of NRAGE promotes autophagy-related gene expression and the periodontitis process in mice.
Haixia LiuXu ZhangQixiang YangXueqin ZhuFubo ChenJing YueRong ZhouYuanzhi XuShengcai QiPublished in: Oral diseases (2020)
The present study showed that knockout of NRAGE induced autophagy-related gene expression and accelerated the process of periodontitis disease via increasing the activity and differentiation of osteoclast.