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Education and Cardiovascular Health as Effect Modifiers of APOE ε4 on Dementia: The Atherosclerosis Risk in Communities (ARIC) Study.

Mark LeeTimothy M HughesKristen M GeorgeMichael E GriswoldSanaz SedaghatJeannette SiminoPamela L Lutsey
Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2021)
Education and cardiovascular health were associated with lower dementia risk regardless of APOE genotype, though the protective effects of education were somewhat diminished among ε4 carriers.
Keyphrases
  • healthcare
  • mild cognitive impairment
  • cognitive decline
  • quality improvement
  • cognitive impairment
  • high fat diet
  • cardiovascular disease
  • type diabetes
  • metabolic syndrome
  • adipose tissue
  • skeletal muscle