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HebbPlot: an intelligent tool for learning and visualizing chromatin mark signatures.

Hani Z GirgisAlfredo VelascoZachary E Reyes
Published in: BMC bioinformatics (2018)
This study resulted in a novel software tool, HebbPlot, for learning and visualizing the chromatin signature of a genetic element. Using HebbPlot, we produced a visual catalog of the signatures of multiple genetic elements in 57 cell types available through the Roadmap Epigenomics Project. Furthermore, we made a progress toward a functional catalog consisting of 22 histone marks. In sum, HebbPlot is applicable to a wide array of studies, facilitating the deciphering of the histone code.
Keyphrases
  • genome wide
  • dna methylation
  • copy number
  • gene expression
  • dna damage
  • transcription factor
  • single cell
  • quality improvement
  • living cells
  • high resolution
  • high throughput
  • stem cells
  • oxidative stress
  • bone marrow