Performance of International AIDS Vaccine Initiative African clinical research laboratories in standardised ELISpot and peripheral blood mononuclear cell processing in support of HIV vaccine clinical trials.
Robert K LangatBashir FarahJackton IndangasiSimon OgolaGloria S Omosa-ManyonyiOmu AnzalaJean BizimanaEmmanuel TekiryaCaroline J NgetsaMoses SilwambaEnoch MuyanjaParamesh ChettyMaureen JanganoNancy K HillsJill GilmourLen DallyJosephine H CoxPeter HayesPublished in: African journal of laboratory medicine (2021)
We demonstrate that multiple laboratories can generate reliable, accurate and comparable data by using standardised procedures, having regular training, having regular equipment maintenance and using centrally sourced reagents.
Keyphrases
- peripheral blood
- antiretroviral therapy
- clinical trial
- hiv infected
- hiv positive
- human immunodeficiency virus
- hiv aids
- hiv testing
- single cell
- cell therapy
- quality improvement
- hepatitis c virus
- high resolution
- men who have sex with men
- big data
- stem cells
- machine learning
- deep learning
- mass spectrometry
- mesenchymal stem cells
- artificial intelligence
- study protocol
- south africa