Detection of brain somatic variation in epilepsy-associated developmental lesions.

Tracy A BedrosianKatherine E MillerOlivia E GrischowKathleen M SchiefferStephanie LaHayeHyojung YoonAnthony R MillerJason NavarroJesse WestfallKristen LeraasSamantha ChoiRachel WilliamsonJames FitchBenjamin J KellyPeter WhiteKristy LeeSean McGrathCatherine E CottrellVincent MagriniJeffrey LeonardJonathan PindrikAmmar ShaikhouniDaniel R BouéDiana L ThomasChristopher R PiersonRichard K WilsonAdam P OstendorfElaine R MardisDaniel C Koboldt

Published in: Epilepsia (2022)

These results further elucidate the genetic basis of structural brain abnormalities leading to focal epilepsy in children and point to new candidate disease genes.

Keyphrases

resting state
white matter
genome wide
copy number
functional connectivity
young adults
cerebral ischemia
multiple sclerosis
loop mediated isothermal amplification
genome wide identification
bioinformatics analysis
quantum dots
genome wide analysis