Prenatal prediction of fetal Rh C, c and E status by amplification of maternal cfDNA and deep sequencing.

Klaus RieneckFrederik Banch ClausenThomas BergholtLone Nikoline NørgaardMorten Hanefeld Dziegiel

Published in: Prenatal diagnosis (2021)

Noninvasive, prenatal prediction of fetal blood groups by sequencing cfDNA for the detection of low-level RHCE*C, RHCE*c and RHCE*E sequences was established as an accurate and robust assay applicable for use in clinical settings.

Keyphrases

pregnant women
single cell
label free
high throughput
high resolution
nucleic acid
birth weight
loop mediated isothermal amplification
real time pcr
body mass index
preterm birth
gestational age
weight gain