Odontoblasts release exosomes to regulate the odontoblastic differentiation of dental pulp stem cells.
Xinghong LuoWeiqing FengShijiang HuangShenghong MiaoTao JiangQian LeiJingyao YinSheng ZhangXiaochun BaiChunbo HaoWeizhong LiDandan MaPublished in: Stem cell research & therapy (2023)
mTORC1 regulates exosome release from odontoblasts to inhibit the odontoblastic differentiation of DPSCs, but it does not alter exosomal contents. These findings might provide a new understanding of dental pulp complex regeneration.