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APOE2 protects against Aβ pathology by improving neuronal mitochondrial function through ERRα signaling.

Zhiyuan NingYing LiuMengyao WanYou ZuoSiqi ChenZhongshan ShiYongteng XuHonghong LiHo KoJing ZhangSonghua XiaoDaji GuoYamei Tang
Published in: Cellular & molecular biology letters (2024)
APOE2 appears to enhance neural mitochondrial function via the activation of ERRα signaling, which may be the protective effect of APOE2 to treat AD.
Keyphrases
  • cognitive decline
  • high fat diet
  • adipose tissue
  • type diabetes
  • metabolic syndrome
  • brain injury