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An integrated method for single cell proteomics with simultaneous measurements of intracellular drug concentration implicates new mechanisms for adaptation to KRAS G12D inhibitors.

Benjamin C Orsburn
Published in: bioRxiv : the preprint server for biology (2023)
Keyphrases
  • single cell
  • rna seq
  • mass spectrometry
  • high throughput
  • wild type
  • reactive oxygen species
  • label free
  • adverse drug
  • drug induced