Five-year Treatment with Tenofovir Alafenamide Achieves High Rates of Viral Suppression, Alanine Aminotransferase Normalization, and Favorable Bone and Renal Safety in Chinese Chronic Hepatitis B Patients.
Jin-Lin HouQin NingZhongping DuanYu ChenQing XieLunli ZhangShanming WuHong TangJun LiFeng LinYongfeng YangGuozhong GongYanwen LuoShelley XieHongyuan WangRoberto MateoTahmineh YazdiFrida AbramovLeland J YeeJohn FlahertyChengwei ChenYan HuangMingxiang ZhangJidong JiaPublished in: Journal of clinical and translational hepatology (2024)
The 5-year TAF treatment efficacy was high and similar to that of 3-year TDF followed by 2-year TAF in Chinese chronic hepatitis B patients. Favorable effects on bone and renal parameters were sustained with TAF treatment alone and were observed following the switch from TDF to TAF.