The Traumatic Inoculation Process Affects TSPO Radioligand Uptake in Experimental Orthotopic Glioblastoma.
Lukas GoldEnio BarciMatthias BrendelMichael OrthJiying ChengSabrina V KirchleitnerLaura M BartosDennis PötterMaximilian A KirchnerLena M UnterrainerLena KaiserSibylle ZieglerLorraine WeidnerMarkus J RiemenschneiderMarcus UnterrainerClaus BelkaJoerg-Christian TonnPeter BartensteinMaximilian NiyaziLouisa von BaumgartenRoland E KälinRainer GlassKirsten LauberNathalie L AlbertAdrien HolzgrevePublished in: Biomedicines (2024)
We identify the inoculation-driven immune response to be a relevant contributor to the PET signal and add a new aspect to consider for planning PET imaging studies in orthotopic glioblastoma models.