Advances and Future Directions of Molecular Breast Imaging.

Molecular breast imaging (MBI) using 99mTc-sestamibi has advanced rapidly over the past decade. Technical advances allow lower dose, higher resolution imaging, and biopsy capability. MBI can be used for supplemental breast cancer screening with mammography for women with dense breasts, neoadjuvant therapy response assessment, extent of disease evaluation, and breast cancer risk prediction. This article highlights the current state-of-the-art and future directions of MBI.