Blood eosinophil count-guided corticosteroid therapy and as a prognostic biomarker of exacerbations of chronic obstructive pulmonary disease: a systematic review and meta-analysis.

Tao LiuZi-Jian XiangXiao-Meng HouJing-Jing ChaiYan-Li YangXiao-Tong Zhang

Published in: Therapeutic advances in chronic disease (2021)

Our research shows that a BEC ⩾ 200 cells/μl or ⩾2% is likely to become the cutoff value of ICS treatment for ECOPD. Moreover, we believe that the baseline BEC can be used as a biomarker for predicting ECOPD. The stability of BEC requires special attention.

Keyphrases

induced apoptosis
chronic obstructive pulmonary disease
cell cycle arrest
cystic fibrosis
working memory
cell death
peripheral blood
oxidative stress
signaling pathway
combination therapy