Ribosomal and non-ribosomal PCR targets for the detection of low-density and mixed malaria infections.
Lara Cotta AmaralDaniela Rocha RobortellaLuiz Felipe Ferreira GuimarãesJean Ezequiel LimongiCor Jesus Fernandes FontesDhelio Batista PereiraCristiana Ferreira Alves de BritoFlora Satiko KanoTaís Nóbrega de SousaLuzia Helena CarvalhoPublished in: Malaria journal (2019)
This study presents a new species-specific non-ribosomal PCR assay with potential to identify low-density P. vivax and P. falciparum infections. As the majority of subclinical infections was caused by P. vivax, the commonest form of malaria in the Amazon area, future studies should investigate the potential of Pvr47/Pfr364 to detect mixed-malaria infections in the field.