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Genotypic diversity and antifungal susceptibility of Scedosporium species from clinical settings in China.

Min ChenXinlin ZhuYang CongHulin ChenQing HouNan HongXinchun ChenWenzhi LeiJie CaiXiuhai LuLihua ShuaiXinhua LiShuwen DengJian-Ping XuWanqing LiaoWeihua PanHeping XuGerrit Sybren de Hoog
Published in: Mycoses (2022)
The genetic diversity of clinical isolates of Scedosporium species from China is extremely high, with S. boydii being predominant and S. aurantiacum being firstly reported here. VOR was the only antifungal compound with low MIC values for all Scedosporium isolates in our study, which should be recommended as the firstline antifungal treatment against scedosporiosis in China.
Keyphrases
  • genetic diversity
  • candida albicans
  • combination therapy
  • replacement therapy