Association of biomarkers of enteric dysfunction, systemic inflammation, and growth hormone resistance with seroconversion to oral rotavirus vaccine: A lasso for inference approach.
Katayi Mwila KazimbayaSamuel BosomprahObvious Nchimunya ChilyabanyamaCaroline Cleopatra ChisengaMwelwa ChibuyeNatasha Makabilo LabanMichelo SimuyandiBert HufferMiren Iturriza-GomaraRobert K M ChoyRoma ChilengiPublished in: PloS one (2023)
MEEDAT successfully measured biomarkers of growth, systemic inflammation, and EED in infants undergoing vaccination, with RBP4 being the only analyte associated with both oral and parenteral rotavirus vaccine responses. Tg and HRP2 were associated with responses to all three serotypes in the parenteral vaccine, while I-FABP and sTfR results indicated possible strain specific immune responses to parenteral immunization.