Impact of HBsAg and HBcrAg levels on phenotype and function of HBV-specific T cells in patients with chronic hepatitis B virus infection.

Elmira AliabadiMelanie Urbanek-QuaingBenjamin MaasoumyBirgit BremerMartin GrasshoffYang LiChristian E NiehausHeiner WedemeyerAnke R M KraftMarkus Cornberg

Published in: Gut (2021)

Our data suggest that age and HBcrAg rather than HBsAg, are associated with HBV-specific T cell responses. Finally, very low antigen levels indicated by HBsAg and in particular HBcrAg may influence T cell response to checkpoint inhibition.

Keyphrases

hepatitis b virus
liver failure
cell cycle
big data
machine learning
data analysis
deep learning
artificial intelligence