Genomic Features of Exceptional Response in Vemurafenib ± Cobimetinib-treated Patients with BRAF V600-mutated Metastatic Melanoma.

Yibing YanMatthew J WongchenkoCaroline RobertJames LarkinPaolo Antonio AsciertoBrigitte DrénoMichele MaioClaus GarbePaul B ChapmanJeffrey A SosmanZhen ShiHartmut KoeppenJessie J HsuIlsung Chang Ivor CaroIsabelle RooneyGrant A McArthurAntoni Ribas

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

These findings suggest that enriched immune infiltration might be a shared feature favoring response to both targeted and immune therapies, while features of innate resistance to targeted and immune therapies were distinct.

Keyphrases

immune response
cancer therapy
deep learning
drug delivery
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