Detection of a knockdown mutation in the voltage-sensitive sodium channel associated with permethrin tolerance in Sarcoptes scabiei var. hominis mites.

K RiebenbauerK PurkhauserJ WalochnikN UrbanP B WeberT StammAlessandra Handisurya

Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2023)

The kdr-associated M918L mutation in the VSSC gene has now emerged in S. scabiei var. hominis mites. Hence, loss of sensitivity to permethrin due to kdr-type resistance may be more prevalent than anticipated and may be decisive for the therapy responsiveness of scabies-infested patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
prognostic factors
genome wide
bone marrow
loop mediated isothermal amplification
replacement therapy