Oral microbiota of patients with phenylketonuria: A nation-based cross-sectional study.

Memduh BingölAlessio CardilliAnne Carolin BingölUlrike LöberCorinna BangAndre FrankeTheodosia BartzelaSkadi BebloEberhard MönchSimone StolzArne S SchaeferSofia Kirke ForslundGesa M Richter

Published in: Journal of clinical periodontology (2024)

PKU patients' reduced microbial diversity may be due to their diet's metabolic challenges disrupting microbial and immune balance, thus increasing oral inflammation. Higher alpha diversity in PKU patients with oral inflammation is likely related to expanded microbial niches.

Keyphrases

microbial community
oxidative stress
end stage renal disease
ejection fraction
newly diagnosed
physical activity
prognostic factors
peritoneal dialysis