Sex-dependent aortic valve pathology in patients with rheumatic heart disease.
Feng XiaoRui ZhengDi YangKejiang CaoShijiang ZhangBingruo WuYongfeng ShaoBin ZhouPublished in: PloS one (2017)
Inflammation is more prominent in aortic valves of female patients with rheumatic heart disease. This sex difference may contribute to the severe valve pathology and worse outcome of female patients.
Keyphrases
- aortic valve
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- aortic valve replacement
- aortic stenosis
- end stage renal disease
- rheumatoid arthritis
- ejection fraction
- pulmonary hypertension
- newly diagnosed
- chronic kidney disease
- prognostic factors
- mitral valve
- heart failure
- pulmonary artery
- early onset
- patient reported outcomes
- atrial fibrillation