In Vitro Assessment of Homeopathic Potencies of Hydrastis canadensis on Hormone-Dependent and Independent Breast Cancer.

Sabiha KhanDebadatta NayakAnil KhuranaRaj Kumar ManchandaChanderdeep TandonSimran Tandon

Published in: Homeopathy : the journal of the Faculty of Homeopathy (2020)

Hydrastis may have a selective cytotoxic effect against hormone-dependent breast cancer MCF 7 cells, leading to cell cycle arrest in the G0/G1 phase, which could be the plausible reason for the induction of apoptosis. The results need to be validated in vivo.

Keyphrases

cell cycle arrest
cell death
pi k akt
signaling pathway
cell proliferation
breast cancer cells
induced apoptosis
oxidative stress
young adults
endoplasmic reticulum stress
breast cancer risk
childhood cancer
clinical evaluation