Changes in the proteome of sea urchin Paracentrotus lividus coelomocytes in response to LPS injection into the body cavity.
Luigi IngugliaMarco ChiaramonteVincenzo ArizzaLilla TuriákKároly VékeyLaszlo DrahosRosa PitonzoGiuseppe AvelloneVita Di StefanoPublished in: PloS one (2020)
Our data demonstrates, through mass spectrometry and the following functional annotation bioinformatics analysis, how the bacterial wall constituent is sufficient to set off an immune response inducing cytoskeleton reorganisation, the appearance of clusters of heat shock proteins (Hsp) and histone proteins and the activation of the endocytic and phagocytic pathways. Data are available via ProteomeXchange with identifier PXD008439.
Keyphrases
- heat shock
- immune response
- bioinformatics analysis
- heat shock protein
- mass spectrometry
- heat stress
- electronic health record
- big data
- liquid chromatography
- inflammatory response
- dna methylation
- high resolution
- data analysis
- gene expression
- machine learning
- anti inflammatory
- ultrasound guided
- toll like receptor
- gas chromatography