Nongenetic Determinants of Risk for Early-Onset Colorectal Cancer.
Alexi N ArchambaultYi LinJihyoun JeonTabitha A HarrisonD Timothy BishopHermann BrennerGraham CaseyAndrew T ChanJenny Chang-ClaudeJane C FigueiredoSteven GallingerStephen B GruberMarc J GunterMichael HoffmeisterMark E JenkinsTemitope O KekuLoïc Le MarchandLi LiVictor MorenoPolly A NewcombRish K PaiPatrick S ParfreyGadi RennertLori C SakodaRobert S SandlerMartha L SlatteryMingyang SongAung-Ko WinMichael O WoodsNeil MurphyPeter T CampbellYu-Ru SuAnne Zeleniuch-JacquottePeter S LiangMengmeng DuLi HsuUlrike PetersRichard B HayesPublished in: JNCI cancer spectrum (2021)
In this large study, we identified several nongenetic risk factors associated with early-onset CRC, providing a basis for targeted identification of those most at risk, which is imperative in mitigating the rising burden of this disease.