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Creating a User-Friendly and Open-Access Gene Expression Database for Comparing Embryonic Development and Regeneration in Nematostella vectensis.

Olivier CroceEric Röttinger
Published in: Methods in molecular biology (Clifton, N.J.) (2022)
The sea anemone Nematostella vectensis has emerged as a powerful research model to understand at the gene regulatory network level, to what extend regeneration recapitulates embryonic development. Such comparison involves massive transcriptomic analysis, a routine approach for identifying differential gene expression. Here we present a workflow to build a user-friendly, mineable, and open-access database providing access to the scientific community to various RNAseq datasets.
Keyphrases
  • gene expression
  • stem cells
  • minimally invasive
  • dna methylation
  • adverse drug
  • low cost
  • healthcare
  • mental health
  • wound healing
  • electronic health record
  • network analysis
  • clinical evaluation