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Klotho Stabilizes the Podocyte Actin Cytoskeleton in Idiopathic Membranous Nephropathy through Regulating the TRPC6/CatL Pathway.

Hongyun WangHongyan LiuHong ChengXue XueYamei GeXiaoqin WangJun Yuan
Published in: American journal of nephrology (2024)
Klotho may protect against podocyte injury in IMN patients by inhibiting the TRPC6/CatL pathway. Klotho is a potential target for reducing proteinuria in IMN patients.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • peritoneal dialysis
  • signaling pathway
  • patient reported outcomes
  • climate change
  • risk assessment
  • patient reported
  • endothelial cells