Immune Checkpoint Inhibition-Related Myasthenia-Myositis-Myocarditis Responsive to Complement Blockade.
Christopher NelkeMarc PawlitzkiRuth KerkhoffChristina B SchroeterOrhan AktasEva Neuen-JacobAmin PolzinSven Guenther MeuthTobias RuckPublished in: Neurology(R) neuroimmunology & neuroinflammation (2023)
Neuromuscular irAEs are associated with a high in-hospital mortality, and specific treatment strategies remain an unmet need. Here, early muscle biopsy enabled targeted therapy after standard approaches failed, thereby highlighting the value of identifying a specific treatment target. To improve therapeutic outcomes, the development of patient-tailored strategies for neuromuscular irAEs requires further studies.