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Immune Checkpoint Inhibition-Related Myasthenia-Myositis-Myocarditis Responsive to Complement Blockade.

Christopher NelkeMarc PawlitzkiRuth KerkhoffChristina B SchroeterOrhan AktasEva Neuen-JacobAmin PolzinSven Guenther MeuthTobias Ruck
Published in: Neurology(R) neuroimmunology & neuroinflammation (2023)
Neuromuscular irAEs are associated with a high in-hospital mortality, and specific treatment strategies remain an unmet need. Here, early muscle biopsy enabled targeted therapy after standard approaches failed, thereby highlighting the value of identifying a specific treatment target. To improve therapeutic outcomes, the development of patient-tailored strategies for neuromuscular irAEs requires further studies.
Keyphrases
  • case report
  • skeletal muscle
  • ultrasound guided
  • smoking cessation
  • type diabetes
  • metabolic syndrome
  • adipose tissue
  • replacement therapy