Human placental extract ameliorates methotrexate-induced hepatotoxicity in rats via regulating antioxidative and anti-inflammatory responses.

Published in: Cancer chemotherapy and pharmacology (2021)

HPE has the ability to ameliorate methotrexate-induced liver injury in rats by mechanisms that include boosting antioxidative responses and down-regulating MDA and pro-inflammatory cytokine production.

Keyphrases

anti inflammatory
high glucose
endothelial cells
drug induced
diabetic rats
high dose
oxidative stress
low dose
cell proliferation
signaling pathway