Human placental extract ameliorates methotrexate-induced hepatotoxicity in rats via regulating antioxidative and anti-inflammatory responses.
Mamdooh H GhoneumMohamed S A El-GerbedPublished in: Cancer chemotherapy and pharmacology (2021)
HPE has the ability to ameliorate methotrexate-induced liver injury in rats by mechanisms that include boosting antioxidative responses and down-regulating MDA and pro-inflammatory cytokine production.