Development and characterization of a Yucatan miniature biomedical pig permanent middle cerebral artery occlusion stroke model.
Simon R PlattShannon P HolmesElizabeth W HowerthKylee Jo J DubersteinC Robert DoveHolly A KinderEmily L WyattAmie V LinvilleVivian W LauSteven L SticeWilliam D HillDavid C HessFranklin D WestPublished in: Experimental & translational stroke medicine (2014)
The MCAO procedure led to significant and consistent strokes with high survivability. These results suggest that the pig model is potentially a robust system for the study of stroke pathophysiology and potential diagnostics and therapeutics.