Status epilepticus and diabetes ketoacidosis: uncommon clinical presentations of acromegaly.
Nyasatu G ChambaAhlam A AmourAbid M SadiqTecla R LyamuyaEmmanuel V AsseyAdnan M SadiqWilliam P HowlettPublished in: Endocrinology, diabetes & metabolism case reports (2021)
Conditions such as status epilepticus and DKA may be clinical presentations in patients presenting with acromegaly. Seizures are rare in people with pituitary adenoma and typically occur when the tumor invades the suprasellar area due to mass effect on the brain. This article shows how best we were able to manage the acromegaly complications in a low resource setting. Hyperprolactinemia in acromegaly may be due to disruption of the normal dopaminergic inhibition of prolactin secretion due to mass effect of the macroadenoma, and around 25% of GH-secreting adenomas co-secrete prolactin.