Measuring the Pancreatic β Cell Mass in Vivo with Exendin SPECT during Hyperglycemia and Severe Insulitis.

Lieke JoostenMaarten BromHanneke PeetersDesirée BosEddy HimpeLuc BouwensOtto BoermanMartin Gotthardt

Published in: Molecular pharmaceutics (2019)

Despite hyperglycemia and severe insulitis, we have found a good correlation between BCM and pancreatic exendin uptake, even in a suboptimal model with relatively high background activity.

Keyphrases

early onset
single cell
cell therapy
diabetic rats
pet ct
drug induced
mesenchymal stem cells