Measuring the Pancreatic β Cell Mass in Vivo with Exendin SPECT during Hyperglycemia and Severe Insulitis.
Lieke JoostenMaarten BromHanneke PeetersDesirée BosEddy HimpeLuc BouwensOtto BoermanMartin GotthardtPublished in: Molecular pharmaceutics (2019)
Despite hyperglycemia and severe insulitis, we have found a good correlation between BCM and pancreatic exendin uptake, even in a suboptimal model with relatively high background activity.