Cellular senescence mediates the detrimental effect of prenatal dexamethasone exposure on postnatal long bone growth in mouse offspring.

Jianwen SuYu ChaiZhiguo JiYongheng XieBin YuXianrong Zhang

Published in: Stem cell research & therapy (2020)

Cellular senescence mediates the toxic effect of PDE on postnatal long bone growth in mouse offspring, and inhibition of cellular senescence may be proposed for treating the retardation of bone growth caused by PDE.

Keyphrases

bone mineral density
endothelial cells
preterm infants
high fat diet
soft tissue
bone loss
stress induced
bone regeneration
low dose
type diabetes
high dose
metabolic syndrome
adipose tissue
oxidative stress
body composition
insulin resistance