Tuberous Sclerosis Complex: Prenatal Diagnosis Using Ultrasound and Magnetic Resonance Imaging-A Report of Two Cases.
Eduardo Félix Martins SantanaAna Maria Faria EstevesDaniella Guerra DelorenzoLuiz Celso Hygino da CruzHeron Werner JuniorAntonio Fernandes MoronPublished in: The Indian journal of radiology & imaging (2022)
Tuberous sclerosis complex (TSC) is a multiple system neurocutaneous syndrome with a genetic disorder caused by different mutations in TSC1 or TSC2. Usually, TSC causes tumors in the heart, brain, kidneys, eyes, and lungs. However, tumors can also develop in any other organs. The prenatal diagnosis of TCS is based on the identification of fetal cardiac tumors by ultrasound and brain subependymal nodules, usually identified by fetal magnetic resonance imaging (MRI). We present two case reports of the prenatal diagnosis of TCS using both ultrasound and MRI, which were confirmed by clinical and radiological methods in the postnatal period accordingly.
Keyphrases
- magnetic resonance imaging
- contrast enhanced
- computed tomography
- diffusion weighted imaging
- resting state
- white matter
- case report
- heart failure
- preterm infants
- functional connectivity
- multiple sclerosis
- cerebral ischemia
- magnetic resonance
- atrial fibrillation
- contrast enhanced ultrasound
- blood brain barrier
- subarachnoid hemorrhage