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[Relapsing-remitting multiple sclerosis: clinical and immunological aspects of the pathology on the example of molecules Sema4D and CD72].

I Y DanchenkoTatiana V BaidinaElena KuklinaT N TrushnikovaI V Nekrasova
Published in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2021)
The use of SemaD as a target in the treatment of RRMS is scientifically substantiated. In case of a positive decision on the use of anti-Sema4D drugs, it will be necessary to take into account the effects of semaphorin not only in the central nervous system, but also in the immune system of patients with RRMS.
Keyphrases
  • multiple sclerosis
  • white matter
  • cerebrospinal fluid
  • decision making
  • combination therapy
  • replacement therapy