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Glycyrrhizic acid suppresses 1,2-dimethylhydrazine-induced colon tumorigenesis in Wistar rats: Alleviation of inflammatory, proliferation, angiogenic, and apoptotic markers.

Rehan KhanMuneeb U RehmanAbdul Quaiyoom KhanMir TahirSarwat Sultana
Published in: Environmental toxicology (2018)
The findings of the study suggest that GA has chemopreventive potential against DMH-induced colon tumorigenesis plausibly through the attenuation of hyperproliferative responses, pro-inflammatory cytokines level, inflammatory and angiogenic markers, and apoptotic responses.
Keyphrases
  • cell death
  • high glucose
  • diabetic rats
  • oxidative stress
  • anti inflammatory
  • signaling pathway
  • climate change
  • stress induced