HLA-B27 may modulate the interaction between ERAP1 polymorphisms and smoking in ankylosing spondylitis patients.
Javier Fernández-TorresYessica Zamudio-CuevasNathalie Montaño-ArmendárizIván Alejandro Luján-JuárezRoberto Sánchez-SánchezKarina Martínez FloresPublished in: Molecular biology reports (2022)
The rs30187 and rs27044 variants of the ERAP1 gene appear to potentiate the effect of smoking in patients with AS carrying the B27 allele.