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Pregnancy in women with multiple sclerosis in France from 2010 to 2015: Incidence, outcomes, and exposure to disease-modifying therapies.

Hélène TillautAdeline DegrémontSandrine KerbratJonathan RouxEmmanuelle Le PageChristelle MainguySolène DurosElisabeth PolardEmmanuelle Leray
Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2021)
In this population-based study, we showed an increase of exposed pregnancies over time, beta-interferon and glatiramer acetate being the most used DMTs and associated with the highest probabilities of live birth. Interrupted exposed pregnancies may reflect undesired pregnancies or fear of an adverse outcome, while recent DMT stop probably reflects pregnancy planning.
Keyphrases
  • preterm birth
  • pregnancy outcomes
  • gestational age
  • multiple sclerosis
  • pregnant women
  • dendritic cells
  • risk factors
  • emergency department
  • type diabetes
  • white matter
  • weight loss
  • skeletal muscle