Diltiazem reduces levels of NT-proBNP and improves symptoms compared with metoprolol in patients with permanent atrial fibrillation.

K Enge Arnljot Tveit S EngerS OnarheimAre Hugo Pripp Peter Selmer Rønningen Magnar G Solberg R Byrkjeland K Andresen A Halsen Hanne Aaserud Aulie Trude Steinsvik C Hall S R Ulimoen

Published in: European heart journal. Cardiovascular pharmacotherapy (2024)

Diltiazem reduced NT-proBNP levels and improved rhythm-related symptoms. Metoprolol increased peptide levels but had no impact on symptoms despite similar heart rate reduction. Non-dihydropyridine calcium channel blockers should be considered more often for rate control in permanent atrial fibrillation.

Keyphrases

heart rate
atrial fibrillation
heart rate variability
blood pressure
heart failure
catheter ablation
left atrial
oral anticoagulants
sleep quality
venous thromboembolism
coronary artery disease
acute coronary syndrome
angiotensin converting enzyme
physical activity