Cardiomyopathy correlates to nerve damage in p.A117S late-onset transthyretin amyloid polyneuropathy.

Yen-Hung LinHsueh-Wen HsuehMao-Yuan SuMei-Fang ChengMing-Chang ChiangJyh-Ming Jimmy JuangYi-Hui KaoKai-Chieh ChangFang-Ping FengSung-Tsang Hsieh Chi-Chao Chao

Published in: Annals of clinical and translational neurology (2022)

Late-onset ATTRv-PN coexisted with cardiomyopathy regardless of the clinical severity of polyneuropathy. The cardiac amyloid burden revealed by CMR was correlated with pathophysiology and clinical disability of nerve degeneration.

Keyphrases

late onset
early onset
heart failure
multiple sclerosis
left ventricular
oxidative stress
risk factors