Effects of metformin, acarbose, and sitagliptin monotherapy on gut microbiota in Zucker diabetic fatty rats.

Minchun ZhangRilu FengMei YangCheng QianZheng WangWei LiuJing Ma

Published in: BMJ open diabetes research & care (2019)

Metformin, acarbose and sitagliptin exerted different effects on the composition of gut microbiota and selectively increased the beneficial bacteria. Supplementation with specific probiotics may further improve the hypoglycemic effects of the antidiabetic drugs.

Keyphrases

type diabetes
combination therapy
open label
wound healing
clinical trial
drug induced