Oral intake of xanthohumol attenuates lipoteichoic acid-induced inflammatory response in human PBMCs.

Finn JungRaphaela StaltnerAmmar TahirAnja BaumannKatharina BurgerEmina HalilbasicClaus HellerbrandIna Bergheim

Published in: European journal of nutrition (2022)

The results of our study suggest that an ingestion of low doses of xanthohumol can suppress the LTA-dependent stimulation of PBMCs through mechanisms involving the interaction of CD14 with TLR2. Study registered at ClinicalTrials.gov (NCT04847193, 22.03.2022).

Keyphrases

inflammatory response
endothelial cells
physical activity
body mass index
weight gain