PGCLCs of human 45,XO reveal pathogenetic pathways of neurocognitive and psychosocial disorders.

Dantong ShangTian LanYue WangXuanyu LiQuanyi LiuHuimin DongBo XuHanhua ChengRongjia Zhou

Published in: Cell & bioscience (2022)

Our data suggest that the specification process of the hPGCLCs in 45,XO, compared to those in 46,XX and 46,XY, enriched pathogenetic pathways that are associated with the onset of neurocognitive and psychosocial disorders.

Keyphrases

mental health
endothelial cells
bipolar disorder
electronic health record
single cell
big data
dna methylation