Prognostic and predictive impact of neutrophil-to-lymphocyte ratio and HLA-I genotyping in advanced esophageal squamous cell carcinoma patients receiving immune checkpoint inhibitor monotherapy.

Lin WangYanrong ZhuBo ZhangXi WangHongnan MoYuchen JiaoJiachen XuJing Huang

Published in: Thoracic cancer (2022)

NLR and HLA-I genotyping could have predictive and prognostic value in patients with advanced ESCC receiving camrelizumab, and the combination of biomarkers may help to identify more patient benefit from immunotherapy.

Keyphrases

genome wide
high throughput
genetic diversity
case report
combination therapy
open label
high density